Ace View of W02D3.9 | |||||||
W02D3.9 Details | |||||||
Description | The unc-37 gene encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO that genetically interacts with components of the transcriptional Mediator complex. | ||||||
Homology Group (KOG) | Transducin-like enhancer of split protein (contains WD40 repeats) |
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GO Terms | negative regulation of transcription (GO:0016481) ; regulation of neurotransmitter levels (GO:0001505) ; synaptic transmission (GO:0007268) ; regulation of synapse structure and function (GO:0050803) ; regulation of axonogenesis (GO:0050770) ; nucleus (GO:0005634) ; transcription co-repressor activity (GO:0003714) ; frizzled signaling pathway (GO:0007222) ; regulation of transcription (GO:0045449) | ||||||
Location | I:6741897..6745740 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
Cenix:13-h5 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | Pnm |
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RNAi Reagent Name & Type | Cenix:13-h5 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: Pronuclear Migration | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
JA:W02D3.9 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
Adult Phenotypes | Unc |
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RNAi Reagent Name & Type | sjj_W02D3.9 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2000-11-16 | ||||||
Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | ||||||
PF:GL1_8H2 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
Adult Phenotypes | Large cytoplasmic granules |
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RNAi Reagent Name & Type | sjj_W02D3.9 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | PCR product contains flanking T7 promoter sequences | ||||||
Laboratory | KK | ||||||
Date | 2002-11-19 | ||||||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | Movies/Stacks/Images | |||||
Simmer:W02D3.9:Screen_A | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
RNAi Reagent Name & Type | sjj_W02D3.9 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Simmer:W02D3.9:Screen_B | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
RNAi Reagent Name & Type | sjj_W02D3.9 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Gene Plot of W02D3.9 | |||||||