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Gene/ORF W02F12.5 Ace View of W02F12.5
W02F12.5 Details Help
Description  This gene encodes a protein predicted by Eisenberg and coworkers, with 68% accuracy, to be mitochondrial.
Homology Group (KOG)  Dihydrolipoamide succinyltransferase (2-oxoglutarate dehydrogenase, E2 subunit)
GO Terms  acyltransferase activity (GO:0008415) ; metabolism (GO:0008152) ; dihydrolipoamide S-succinyltransferase activity (GO:0004149) ; tricarboxylic acid cycle (GO:0006099) ; oxoglutarate dehydrogenase complex (GO:0045252)
Location   V:6709074..6712097
RNAi Phenotypes
Early_embryo Severe Pleiotropic Defects
Larva Lva ; Lva ; Gro
Adult Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:27-h12 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Embryonic Phenotypes  Emb Penetrance 100 %
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_W02F12.5 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Embryonic Phenotypes  Emb Penetrance 50 - 80 %
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_W02F12.5 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of W02F12.5 Browse using GBrowse
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