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Gene/ORF W03C9.3 (rab-7) Ace View of W03C9.3
W03C9.3 Details Help
Description  rab-7 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; RAB-7 is required for proper yolk protein localization in oocytes, and for embryogenesis, locomotion, and normal body morphology; by sequence similarity, RAB-7 is predicted to be a late endosome component.
Homology Group (KOG)  Ras-related GTPase
GO Terms  endocytosis (GO:0006897) ; oocyte growth (GO:0001555) ; cellular_component unknown (GO:0008372) ; GTPase activity (GO:0003924) ; GTP binding (GO:0005525) ; small GTPase mediated signal transduction (GO:0007264) ; protein transport (GO:0015031) ; DNA binding (GO:0003677) ; two-component signal transduction system (phosphorelay) (GO:0000160) ; regulation of transcription, DNA-dependent (GO:0006355)
Location   II:11964727..11967238
RNAi Phenotypes
Early_embryo Integrity of Membranous Organelles defective ; Cytokinesis problems
Postembryonic Prz
Adult Dpy ; Dpy ; Bmd ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
[cgc5655]:tub-1:W03C9.3 WT
[cgc5655]:daf-2:W03C9.3 WT
Experiments with Non-Wild Phenotypes
Cenix:143-e7 Emb ; Integrity of Membranous Organelles defective
[cgc5655]:tph-1:W03C9.3 Unclassified
Simmer:W03C9.3 Dpy ; Emb ; Unc
[cgc5655]:W03C9.3 Unclassified
JA:W03C9.3 Bmd ; Dpy ; Emb ; Prz
Gene Plot of W03C9.3 Browse using GBrowse
Gene Map