Ace View of W06F12.1 | |||||||
W06F12.1 Details | |||||||
Description | lit-1 encodes a serine threonine protein kinase homolog related to the Drosophila protein Nemo that is required for embryonic viability, plays a central role in controlling the asymmetry of cell divisions during embryogenesis, and affects EMS, MS, and C lineages; acts downstream of mom-2 with respect to polarity defects and mediates larval cell fate decisions that involve POP-1, and is expressed in most embryonic and larval cells. | ||||||
GO Terms | asymmetric cytokinesis (GO:0008356) ; embryonic development (GO:0009790) ; Wnt receptor signaling pathway (GO:0016055) ; protein serine/threonine kinase activity (GO:0004674) ; kinase activity (GO:0016301) ; MAP kinase activity (GO:0004707) ; ATP binding (GO:0005524) ; protein amino acid phosphorylation (GO:0006468) ; protein kinase activity (GO:0004672) ; protein-tyrosine kinase activity (GO:0004713) | ||||||
Location | III:13701109..13724317 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
JA:W06F12.1 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
RNAi Reagent Name & Type | sjj_W06F12.1 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2003-1-10 | ||||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||
Simmer:W06F12.1 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
RNAi Reagent Name & Type | sjj_W06F12.1 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
TH:321A8 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
RNAi Reagent Name & Type | TH:321A8 (PCR reagent) | ||||||
Remark | Phenotype comment -- Not yet confirmed by independent RNA | ||||||
Laboratory | TH | ||||||
Date | 2000-11-16 | ||||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||
Cenix:321-a8 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | WT_postembryonic_morphology |
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RNAi Reagent Name & Type | Cenix:321-a8 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
Gene Plot of W06F12.1 | |||||||