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Gene/ORF W08D2.4 (fat-3) Ace View of W08D2.4
W08D2.4 Details Help
Description  The fat-3 gene encodes a delta-6 fatty acid desaturase ('linoleoyl-CoA desaturase') containing an N-terminal cytochrome b5 domain; FAT-3 expressed in yeast uses linoleic and alpha-linolenic acid as substrates; FAT-3 is absolutely required in vivo for synthesis of delta-6 fatty acids, and also required for fully normal synthesis of C20 fatty acids; FAT-3 is required for a normally fast growth rate and movement speed, and for normal defecation rhythms and fertility.
Homology Group (KOG)  Delta 6-fatty acid desaturase/delta-8 sphingolipid desaturase
GO Terms  oxidoreductase activity (GO:0016491) ; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (GO:0016717) ; fatty acid desaturation (GO:0006636) ; membrane (GO:0016020) ; transporter activity (GO:0005215) ; binding (GO:0005488) ; transport (GO:0006810)
Location   IV:9802611..9806495
RNAi Phenotypes
Larva Gro
Adult Dpy ; Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Cenix:20-d10 WT
Experiments with Non-Wild Phenotypes
JA:W08D2.4 Dpy ; Gro ; Unc
Simmer:W08D2.4 Unc
Gene Plot of W08D2.4 Browse using GBrowse
Gene Map