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Gene/ORF W10G6.3 (mua-6) Ace View of W10G6.3
W10G6.3 Details Help
Description  mua-6 encodes an essential intermediate filament protein (MUA-6/IFA-2) that is coexpressed with the essential IF protein IFB-1; MUA-6 is required for hypodermal integrity and for lasting attachment of muscles to the body wall; MUA-6 is also required for normal positioning of excretory canals and muscles; MUA-6 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; mua-6 is transcribed from L1 larval to adult stages; MUA-6 resides in main body hypodermal desmosomes, but not in seam cells.
Homology Group (KOG)  Nuclear envelope protein lamin, intermediate filament superfamily
GO Terms  structural molecule activity (GO:0005198)
Location   X:16261804..16266001
RNAi Phenotypes
Postembryonic Prz ; Prl ; Larval Lethal-Late (L3/L4)
Larva Mlt ; Lvl ; Lvl ; Lvl ; Gro
Adult Egl ; Sck ; Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
JA:W10G6.3 Lvl ; Mlt ; Unc
Cenix:56-d7 Larval Lethal-Late (L3/L4)
Simmer:W10G6.3 Gro ; Lvl ; Prz
Gene Plot of W10G6.3 Browse using GBrowse
Gene Map