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Gene/ORF Y111B2A.18 (rsp-3) Ace View of Y111B2A.18
Y111B2A.18 Details Help
Description  rsp-3 encodes a putative ortholog of human SF2/ASF and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation; rsp-3 affects the development of oocytes together with rsr-1, and is required for late embryonic viability; SPK-1 binds directly to and phosphorylates the RS domain of RSP-3 in vitro and the mRNA of rsp-3 is predominantly expressed in the germline.
Homology Group (KOG)  Alternative splicing factor ASF/SF2 (RRM superfamily)
GO Terms  mRNA processing (GO:0006397) ; mRNA splice site selection (GO:0006376) ; embryonic development (sensu Animalia) (GO:0009792) ; nucleotide binding (GO:0000166) ; nucleic acid binding (GO:0003676)
Location   III:12685728..12688197
RNAi Phenotypes
Postembryonic WT_postembryonic_morphology ; WT_postembryonic_morphology ; Larval Lethal-Early (L1/L2)
Larva Lva
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
TH:337F9 WT
Experiments with Non-Wild Phenotypes
JA:Y111B2D.h Emb
Cenix:333-b2 Larval Lethal-Early (L1/L2)
Simmer:Y111B2D.h Emb
Cenix:76-d7 Emb ; WT_postembryonic_morphology
Cenix:337-f9 Emb ; WT_postembryonic_morphology
Gene Plot of Y111B2A.18 Browse using GBrowse
Gene Map