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Gene/ORF Y113G7B.5 (fog-2) Ace View of Y113G7B.5
Y113G7B.5 Details Help
Description  The fog-2 gene encodes a novel protein, with an N-terminal F-box and a C-terminal FTH domain, that is required for hermaphrodite spermatogenesis; FOG-2 interacts with the RNA-binding protein GLD-1 and the tra-2 3' untranslated region to translationally repress tra-2 expression in the hermaphrodite germ line and thus allow for a brief period of spermatogenesis.
GO Terms  hermaphrodite germ-line sex determination (sensu Nematoda) (GO:0042005) ; spermatogenesis (GO:0007283) ; negative regulation of translation (GO:0016478) ; cytoplasm (GO:0005737) ; translation repressor activity (GO:0030371) ; protein binding (GO:0005515)
Location   V:20196861..20198974
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:245-e3 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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