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Gene/ORF Y18D10A.6 (nhx-8) Ace View of Y18D10A.6
Y18D10A.6 Details Help
Description  nhx-8 encodes two isoforms of a sodium/proton exchanger expressed intracellularly within hypodermal seam cells, pharyngeal muscles, pharyngeal-intestinal and intestinal-rectal valve cells, and vulval cells; nhx-8 has no obvious phenotype in mass RNAi screens; NHX-8 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton.
GO Terms  solute:hydrogen antiporter activity (GO:0015299) ; regulation of pH (GO:0006885) ; integral to membrane (GO:0016021) ; sodium:hydrogen antiporter activity (GO:0015385) ; sodium ion transport (GO:0006814)
Location   I:12824828..12834530
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:80-g12
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:80-g12 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wt
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:Y18D10A.6
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_Y18D10A.6 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
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