Ace View of Y38A8.2 | |||||||||
Y38A8.2 Details | |||||||||
Description | pbs-3 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-3 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-3 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-3 is required for embryonic and germline development, movement, normal body coloration, and normal body morphology. | ||||||||
Homology Group (KOG) | 20S proteasome, regulatory subunit beta type PSMB3/PUP3 |
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GO Terms | endopeptidase activity (GO:0004175) ; ubiquitin-dependent protein catabolism (GO:0006511) ; proteasome core complex (sensu Eukarya) (GO:0005839) ; threonine endopeptidase activity (GO:0004298) | ||||||||
Location | II:4954086..4955815 | ||||||||
RNAi Phenotypes |
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External Links | |||||||||
Associated RNAi Experiments | |||||||||
Experiments with Non-Wild Phenotypes | |||||||||
Simmer:Y38A8.2 | Emb | ||||||||
Cenix:151-f7 | Emb ; Passage Through Meiosis defective | ||||||||
JA:Y38A8.2 | Clr ; Emb ; Pch ; Ste ; Unc | ||||||||
Gene Plot of Y38A8.2 | |||||||||