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Gene/ORF Y38A8.2 (pbs-3) Ace View of Y38A8.2
Y38A8.2 Details Help
Description  pbs-3 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-3 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-3 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-3 is required for embryonic and germline development, movement, normal body coloration, and normal body morphology.
Homology Group (KOG)  20S proteasome, regulatory subunit beta type PSMB3/PUP3
GO Terms  endopeptidase activity (GO:0004175) ; ubiquitin-dependent protein catabolism (GO:0006511) ; proteasome core complex (sensu Eukarya) (GO:0005839) ; threonine endopeptidase activity (GO:0004298)
Location   II:4954086..4955815
RNAi Phenotypes
Early_embryo Passage Through Meiosis defective
Postembryonic Pch
Larva Lvl
Adult Clr ; Unc ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Simmer:Y38A8.2 Emb
Cenix:151-f7 Emb ; Passage Through Meiosis defective
JA:Y38A8.2 Clr ; Emb ; Pch ; Ste ; Unc
Gene Plot of Y38A8.2 Browse using GBrowse
Gene Map