Ace View of Y39A1B.3 | |||||
Y39A1B.3 Details | |||||
Description | dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1. | ||||
Homology Group (KOG) | Chromosome condensation complex Condensin, subunit D2 |
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GO Terms | binding (GO:0005488) ; mitosis (GO:0007067) ; chromosome condensation (GO:0030261) ; nucleus (GO:0005634) | ||||
Location | III:10762624..10777204 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Cenix:321-g8 | |||||
RNAi Reagent Name & Type | Cenix:321-g8 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | early embryonic: No significant defects. 1/5 embryos is osmotic sensitive. | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
Cenix:337-b10 | |||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:337-b10 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | wild type | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
JA:Y39A1B.3 | |||||
Embryonic Phenotypes | Emb Penetrance 10 % | ||||
Adult Phenotypes | Dpy Unc |
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RNAi Reagent Name & Type | sjj_Y39A1B.3 (PCR reagent) | ||||
Laboratory | JA | ||||
Date | 2003-1-10 | ||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||
Simmer:Y39A1B.3 | |||||
Embryonic Phenotypes | Emb Penetrance 20 - 40 % | ||||
Larval Phenotypes | Gro |
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Adult Phenotypes | Dpy |
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RNAi Reagent Name & Type | sjj_Y39A1B.3 (PCR reagent) | ||||
Laboratory | NL | ||||
Date | 2003-10-01 | ||||
Strain | NL4256 rrf-3(pk1426) | ||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||
TH:321G8 | |||||
Adult Phenotypes | Dpy |
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RNAi Reagent Name & Type | TH:321G8 (PCR reagent) | ||||
Remark | Phenotype comment -- Not yet confirmed by independent RNA | ||||
Laboratory | TH | ||||
Date | 2000-11-16 | ||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||
TH:337B10 | |||||
Adult Phenotypes | WTDIC phenotype -- Embryonic development normal |
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RNAi Reagent Name & Type | TH:337B10 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Laboratory | TH | ||||
Date | 2000-11-16 | ||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||
Gene Plot of Y39A1B.3 | |||||