Ace View of Y42G9A.4 | |||||
Y42G9A.4 Details | |||||
Description | The Y42G9A.4 gene encodes an ortholog of the human gene MEVALONATE KINASE (MVK), which when mutated leads to mevalonicaciduria (OMIM:251170). | ||||
GO Terms | ATP binding (GO:0005524) ; kinase activity (GO:0016301) ; phosphorylation (GO:0016310) ; phosphotransferase activity, alcohol group as acceptor (GO:0016773) ; metabolism (GO:0008152) ; cytoplasm (GO:0005737) ; mevalonate kinase activity (GO:0004496) ; biosynthesis (GO:0009058) | ||||
Location | III:6124385..6136616 | ||||
RNAi Phenotypes |
|
||||
External Links | |||||
Associated RNAi Experiments | |||||
Cenix:332-e11 | |||||
Adult Phenotypes | WT |
||||
RNAi Reagent Name & Type | Cenix:332-e11 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | wild type | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
JA:Y42G9A.c | |||||
Embryonic Phenotypes | Emb Penetrance 40 % | ||||
Adult Phenotypes | Clr Unc |
||||
RNAi Reagent Name & Type | sjj_Y42G9A.c (PCR reagent) | ||||
Laboratory | JA | ||||
Date | 2003-1-10 | ||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||
Simmer:Y42G9A.c | |||||
Larval Phenotypes | Lva |
||||
Adult Phenotypes | Unc |
||||
RNAi Reagent Name & Type | sjj_Y42G9A.c (PCR reagent) | ||||
Laboratory | NL | ||||
Date | 2003-10-01 | ||||
Strain | NL4256 rrf-3(pk1426) | ||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||
Gene Plot of Y42G9A.4 | |||||