Ace View of Y46H3A.3 | |
Y46H3A.3 Details | |
Description | hsp-16.2 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; hsp-16.2 expression, strongest in intestine and pharynx, is induced in response to heat shock or other environmental stresses; HSP-16.2 has been shown to interact with intracellular human beta amyloid peptide, a primary component of the extracellular plaques found in Alzheimer's disease; HSP-16.2 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating. |
Homology Group (KOG) | Alpha crystallins |
Location | V:1803762..1805152 |
RNAi Phenotypes | No phenotypes observed. |
External Links | |
Associated RNAi Experiments | |
Cenix:235-a12 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | Cenix:235-a12 (PCR reagent) |
Delivery Method | Injection |
Remark | Wildtype results in all three tests. |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
JA:Y46H3A.d | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | sjj_Y46H3A.d (PCR reagent) |
Laboratory | JA |
Date | 2003-1-10 |
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Gene Plot of Y46H3A.3 | |