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Gene/ORF Y48B6A.4 (eat-2) Ace View of Y48B6A.4
Y48B6A.4 Details Help
Description  eat-2 encodes a beta subunit of the nicotinic acetylcholine receptor (nAChR) superfamily which encode ligand-gated ion channels that regulate fast action of acetylcholine at neuromuscular junctions and in the nervous system; EAT-2 regulates the rate of pharyngeal pumping by by affecting MC pharyngeal neuron transmission, and is required for neurotransmission from the MC pharyngeal neuron to pharyngeal muscle, in which it is expressed, and also affects life span and defecation; eat-2 genetically interacts with eat-18, which encodes a predicted transcriptional activator also expressed in pharyngeal muscle.
Homology Group (KOG)  Acetylcholine receptor
GO Terms  neurotransmitter receptor activity (GO:0030594) ; ion transport (GO:0006811) ; membrane (GO:0016020) ; extracellular ligand-gated ion channel activity (GO:0005230) ; transport (GO:0006810) ; integral to membrane (GO:0016021) ; postsynaptic membrane (GO:0045211) ; nicotinic acetylcholine-activated cation-selective channel activity (GO:0004889) ; ion channel activity (GO:0005216)
Location   II:14166375..14171941
RNAi Phenotypes
Larva Lva ; Lvl
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Cenix:229-c9 WT
JA:Y48B6A.4 WT
Experiments with Non-Wild Phenotypes
Simmer:Y48B6A.4:Screen Emb ; Lva ; Lvl
Gene Plot of Y48B6A.4 Browse using GBrowse
Gene Map