Ace View of Y48G1A.5 | |||||||
Y48G1A.5 Details | |||||||
Description | imb-5 encodes an importin-beta-like protein orthologous to mammalian CAS proteins (cellular apoptosis susceptibility) and Saccharomyces cerevisiae CSE1 (chromosome segregation 1); IMB-5 is predicted to function in nuclear transport of proteins required for mitotic progression or apoptosis as well as in re-export of importin-alpha, a nuclear import protein; in C. elegans, IMB-5 is essential for embryogenesis and required for normal pronuclear envelope dynamics, and may also play a role in vulval morphogenesis. | ||||||
Homology Group (KOG) | Nuclear export receptor CSE1/CAS (importin beta superfamily) |
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GO Terms | binding (GO:0005488) ; importin-alpha export receptor activity (GO:0008262) ; apoptosis (GO:0006915) ; cell proliferation (GO:0008283) ; nucleus (GO:0005634) ; cytoplasm (GO:0005737) ; protein transporter activity (GO:0008565) ; protein-nucleus import, docking (GO:0000059) ; nuclear pore (GO:0005643) | ||||||
Location | I:318152..323753 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
Experiments with Non-Wild Phenotypes | |||||||
Simmer:Y48G1A_54.c:Screen_B | Emb | ||||||
Simmer:Y48G1A_54.b:Screen_A | Emb ; Sck ; Ste ; Unc | ||||||
JA:Y48G1A_54.b | Emb ; Pna | ||||||
JA:Y48G1A_54.c | Emb ; Pna ; Pvl | ||||||
Simmer:Y48G1A_54.b:Screen_B | Emb | ||||||
Cenix:152-a8 | Emb ; Pronuclear/Nuclear Appearance abnormal | ||||||
Simmer:Y48G1A_54.c:Screen_A | Emb ; Gro ; Unc | ||||||
Gene Plot of Y48G1A.5 | |||||||