Ace View of Y49E10.1 | |||||||||
Y49E10.1 Details | |||||||||
Description | rpt-6 encodes a triple A ATPase that is a subunit of the 26S proteasome 19S regulatory particle (RP) base subcomplex; RPT-6 is required for embryonic and larval development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome. | ||||||||
Homology Group (KOG) | 26S proteasome regulatory complex, ATPase RPT6 |
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GO Terms | hydrolase activity (GO:0016787) ; protein catabolism (GO:0030163) ; nucleus (GO:0005634) ; cytoplasm (GO:0005737) ; nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; ATP binding (GO:0005524) | ||||||||
Location | III:12369931..12372892 | ||||||||
RNAi Phenotypes |
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External Links | |||||||||
Associated RNAi Experiments | |||||||||
Experiments with Non-Wild Phenotypes | |||||||||
Cenix:331-g6 | Emb ; Sister Chromatid Separation abnormal (Cross-eyed) | ||||||||
TH:341D12 | Emb | ||||||||
TH:331G6 | Emb | ||||||||
Cenix:341-d12 | Larval Lethal-Early (L1/L2) | ||||||||
Simmer:Y49E10.1 | Emb ; Lva ; Unc | ||||||||
Gene Plot of Y49E10.1 | |||||||||