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Gene/ORF Y49E10.14 (pie-1) Ace View of Y49E10.14
Y49E10.14 Details Help
Description  pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6.
Homology Group (KOG)  CCCH-type Zn-finger protein
GO Terms  cell fate determination (GO:0001709) ; formation of primary germ layer (GO:0001704) ; negative regulation of transcription (GO:0016481) ; embryonic pattern specification (GO:0009880) ; nucleus (GO:0005634) ; centrosome (GO:0005813) ; general transcriptional repressor activity (GO:0016565) ; nucleic acid binding (GO:0003676)
Location   III:12426368..12429450
RNAi Phenotypes
Postembryonic WT_postembryonic_morphology
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
TH:340E4 WT
TH:331B9 WT
Experiments with Non-Wild Phenotypes
Cenix:340-e4
Cenix:331-b9 Emb ; WT_postembryonic_morphology
Simmer:Y49E10.14 Emb
JA:Y49E10.14 Emb
Gene Plot of Y49E10.14 Browse using GBrowse
Gene Map