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Gene/ORF Y54E5B.3 (let-49) Ace View of Y54E5B.3
Y54E5B.3 Details Help
Description  let-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1.
Homology Group (KOG)  Transcriptional coactivator
GO Terms  transcription co-activator activity (GO:0003713) ; positive regulation of transcription (GO:0045941) ; nucleus (GO:0005634)
Location   I:14820008..14821978
RNAi Phenotypes
Postembryonic WT_postembryonic_morphology
Larva Gro ; Gro
Adult Dpy ; Dpy ; Pvl ; Pvl ; Unc ; Rup ; Stp ; Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Simmer:Y54E5B.3:Screen_B Dpy ; Emb ; Gro ; Pvl ; Stp ; Unc
JA:Y54E5B.3 Emb ; Led ; Rup
Simmer:Y54E5B.3:Screen_A Dpy ; Gro ; Pvl ; Stp
Cenix:34-c8 Emb ; WT_postembryonic_morphology
Gene Plot of Y54E5B.3 Browse using GBrowse
Gene Map