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Gene/ORF Y57A10A.11 (rol-1) Ace View of Y57A10A.11
Y57A10A.11 Details Help
Description  rol-1 encodes a nematode cuticular collagen required for normal body morphology at the adult stage of development; rol-1 expression is under the control of the heterochronic pathway, as heterochronic mutants that synthesize adult cuticle early produce animals that roll as larvae, while heterochronic mutants that fail to execute normal adult development never display the roller phenotype.
Homology Group (KOG)  Collagens (type IV and type XIII), and related proteins
GO Terms  structural constituent of cuticle (GO:0042302) ; phosphate transport (GO:0006817) ; cytoplasm (GO:0005737)
Location   II:12172078..12176360
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:65-e11
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:65-e11 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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