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Gene/ORF Y66A7A.6 (gly-8) Ace View of Y66A7A.6
Y66A7A.6 Details Help
Description  gly-8 encodes a predicted transmembrane polypeptide N-acetylgalactosaminyl transferase (ppGaNTase) similar to the essential Drosophila ppGaNTase encoded by Pgant35A; by homology, GLY-8 is predicted to function as a Golgi enzyme that catalyzes transfer of N-acetylgalactosamine to serine and threonine-containing acceptor peptides, thus initiating mucin-type O-glycosylation; as loss of gly-8 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GLY-8 in C. elegans development and/or behavior is not yet known.
Homology Group (KOG)  Polypeptide N-acetylgalactosaminyltransferase
Location   III:11624467..11628514
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:321-a10
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:321-a10 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C37G2.6
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_C37G2.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:Y66A7A.6
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_Y66A7A.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
TH:215-b7
RNAi Reagent Name & Type TH:215-b7 (PCR reagent)
TH:321A10
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:321A10 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
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