| Ace View of Y75B8A.2 | |||||||
| Y75B8A.2 Details | |||||||
| Description | The nob-1 gene encodes one of three C. elegans posterior group homeodomain transcription factors orthologous to Drosophila Abd-B and the vertebrate Hox9-13 proteins; NOB-1, along with an additional posterior Hox ortholog, PHP-3, is required during embryogenesis for proper fate specification and morphogenesis of cells in the posterior region. | ||||||
| Homology Group (KOG) | Transcription factor Abd-B, contains HOX domain |
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| GO Terms | embryonic body morphogenesis (GO:0010172) ; tail tip morphogenesis (sensu Nematoda) (GO:0045138) ; embryonic pattern specification (GO:0009880) ; anterior/posterior pattern formation (GO:0009952) ; DNA binding (GO:0003677) ; transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634) ; regulation of transcription (GO:0045449) | ||||||
| Location | III:12077264..12084592 | ||||||
| RNAi Phenotypes |
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| External Links |    |
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| Associated RNAi Experiments | |||||||
| Cenix:331-c12 | |||||||
| RNAi Reagent Name & Type | Cenix:331-c12 (PCR reagent) | ||||||
| Delivery Method | Injection | ||||||
| Remark | post-embryonic: Adult Phenotype-Other | ||||||
| Laboratory | TH | ||||||
| Date | 2005-3-24 | ||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
| JA:Y75B8A.2 | |||||||
| Embryonic Phenotypes | Emb Penetrance 80 % | ||||||
| Adult Phenotypes | Bmd |
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| RNAi Reagent Name & Type | sjj_Y75B8A.2 (PCR reagent) | ||||||
| Laboratory | JA | ||||||
| Date | 2003-1-10 | ||||||
| Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||
| Simmer:Y75B8A.2 | |||||||
| Embryonic Phenotypes | Emb Penetrance 20 - 40 % | ||||||
| Larval Phenotypes | Gro |
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| Adult Phenotypes | Bmd |
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| RNAi Reagent Name & Type | sjj_Y75B8A.2 (PCR reagent) | ||||||
| Laboratory | NL | ||||||
| Date | 2003-10-01 | ||||||
| Strain | NL4256 rrf-3(pk1426) | ||||||
| Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
| TH:331C12 | |||||||
| Adult Phenotypes | Bmd |
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| RNAi Reagent Name & Type | TH:331C12 (PCR reagent) | ||||||
| Remark | Phenotype comment -- Not yet confirmed by independent RNA | ||||||
| Laboratory | TH | ||||||
| Date | 2000-11-16 | ||||||
| Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||
| Gene Plot of Y75B8A.2 | |||||||
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