ORF Card Page

Gene/ORF Y75B8A.2 (nob-1)

Y75B8A.2 Details

Description

The nob-1 gene encodes one of three C. elegans posterior group homeodomain transcription factors orthologous to Drosophila Abd-B and the vertebrate Hox9-13 proteins; NOB-1, along with an additional posterior Hox ortholog, PHP-3, is required during embryogenesis for proper fate specification and morphogenesis of cells in the posterior region.

Homology Group (KOG)

Transcription factor Abd-B, contains HOX domain

GO Terms

embryonic body morphogenesis (GO:0010172) ; tail tip morphogenesis (sensu Nematoda) (GO:0045138) ; embryonic pattern specification (GO:0009880) ; anterior/posterior pattern formation (GO:0009952) ; DNA binding (GO:0003677) ; transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634) ; regulation of transcription (GO:0045449)

Location

III:12077264..12084592

RNAi Phenotypes