Ace View of Y75B8A.26 | |
Y75B8A.26 Details | |
Description | mrp-8 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCC subfamily of ABC transporters that includes the multidrug resistance-associated proteins and the cystic fibrosis transmembrane conductance regulator; by homology, MRP-8 is predicted to function as an ATP-dependent organic anion transporter that transports molecules across the plasma membrane into the extracellular space; at present, the precise role of MRP-8 in C. elegans development and/or behavior is not yet known. |
Homology Group (KOG) | Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily |
GO Terms | nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; ATP binding (GO:0005524) ; ATPase activity, coupled to transmembrane movement of substances (GO:0042626) ; transport (GO:0006810) ; integral to membrane (GO:0016021) ; ATPase activity (GO:0016887) |
Location | III:12282683..12295285 |
RNAi Phenotypes | No phenotypes observed. |
External Links | |
Associated RNAi Experiments | |
Cenix:333-a9 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | Cenix:333-a9 (PCR reagent) |
Delivery Method | Injection |
Remark | wild type |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Gene Plot of Y75B8A.26 | |