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Gene/ORF ZC168.4 (cyb-1) Ace View of ZC168.4
ZC168.4 Details Help
Description  cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage.
Homology Group (KOG)  Cyclin B and related kinase-activating proteins
GO Terms  regulation of cell cycle (GO:0000074) ; nucleus (GO:0005634)
Location   IV:10734914..10737547
RNAi Phenotypes
Early_embryo Abnormal size of pronucleus ; Multiple maternal pronuclei ; Chromosome Segregation (karyomeres) abnormal ; Polar bodies abnormal ; Multiple nuclei in 1, 2, or 4-cell embryos ; Division axis of ABa or ABp aberrant
Larva Lva
Adult Ooc ; Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:10-e7
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Chromosome Segregation (karyomeres) abnormal
RNAi Reagent Name & Type Cenix:10-e7 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Chromosome Segregation (karyomeres)
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:ZC168.4
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_ZC168.4 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_4C6
Embryonic Phenotypes  Emb Penetrance 80 - 100 %
Larval Phenotypes  Lva Observed in >=10% of progeny.
Adult Phenotypes  Stp Observed in <10% of progeny.
Adult Phenotypes  Abnormal size of pronucleus
Division axis of ABa or ABp aberrant
Multiple maternal pronuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Polar bodies abnormal
RNAi Reagent Name & Type sjj_ZC168.4 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Gene Plot of ZC168.4 Browse using GBrowse
Gene Map