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Gene/ORF ZC308.1 (gld-2) Ace View of ZC308.1
ZC308.1 Details Help
Description  gld-2 encodes the catalytic subunit of a cytoplasmic poly(A) polymerase (PAP) associated with P granules in early embryos, which encodes the central catalytic domain but lacks the normal RNA-binding (RRM) domain of eukaryotic PAPs; GLD-2 regulates the switch from mitosis to meiosis in the germline, is necessary for formation of functional sperm or oocytes, requires activation by GLD-3 for PAP activity in vitro, and contains a glutamine/asparagine-rich domain perhaps involved in epigenetic gene control.
GO Terms  nucleic acid binding (GO:0003676)
Location   I:6369567..6386545
RNAi Phenotypes
Early_embryo Osmotic Integrity defective ; Passage Through Meiosis defective
Larva Gro
Adult Sterile F0/Fertility Problems ; Ste ; Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
JA:ZC308.2 WT
Cenix:233-g11 WT
Experiments with Non-Wild Phenotypes
Simmer:ZC308.1:Screen_A Emb ; Ste
Simmer:ZC308.1:Screen_B Emb
JA:ZC308.3 Emb
Simmer:ZC308.2:Screen_A Emb
Cenix:100-d5 Emb ; Passage Through Meiosis defective
Simmer:ZC308.2:Screen_B Emb
Simmer:ZC308.3:Screen_A Emb ; Ste
Simmer:ZC308.3:Screen_B Emb
JA:ZC308.1 Emb ; Gro
Cenix:233-f11 Osmotic Integrity defective ; Sterile F0/Fertility Problems
Gene Plot of ZC308.1 Browse using GBrowse
Gene Map