Ace View of ZK1248.6 | |||
ZK1248.6 Details | |||
Description | msp-64 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | ||
GO Terms | structural molecule activity (GO:0005198) | ||
Location | II:5809490..5810708 | ||
RNAi Phenotypes |
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External Links | |||
Associated RNAi Experiments | |||
Cenix:13-c7 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:13-c7 (PCR reagent) | ||
Delivery Method | Injection | ||
Remark | early embryonic: Clear cut result. | ||
Laboratory | TH | ||
Date | 2005-3-24 | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
JA:ZK1248.6 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_ZK1248.6 (PCR reagent) | ||
Laboratory | JA | ||
Date | 2003-1-10 | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Gene Plot of ZK1248.6 | |||