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Gene/ORF ZK256.1 (pmr-1) Ace View of ZK256.1
ZK256.1 Details Help
Description  The pmr-1 gene encodes a Golgi P-type ATPase Ca^2+/Mn^2+-pump; mutations in its human ortholog, ATP2C1, cause Hailey-Hailey disease (OMIM:169600).
Homology Group (KOG)  Ca2+ transporting ATPase
GO Terms  calcium-transporting ATPase activity (GO:0005388) ; calcium ion transport (GO:0006816) ; integral to membrane (GO:0016021) ; ATP binding (GO:0005524) ; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (GO:0015662) ; cation transport (GO:0006812) ; membrane (GO:0016020) ; catalytic activity (GO:0003824) ; metabolism (GO:0008152) ; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (GO:0016820) ; proton transport (GO:0015992)
Location   I:13004023..13024006
RNAi Phenotypes
Postembryonic Stress Resistance ; Stress Resistance ; Stress Resistance ; Stress Resistance
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:55-f1 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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