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Gene/ORF ZK287.5 (rbx-1) Ace View of ZK287.5
ZK287.5 Details Help
Description  The rbx-1 gene encodes an ortholog of the mammalian RING box protein RBX1 (or ROC1), which interacts with several cullins and is a subunit of both the von Hippel-Lindau (VHL) tumor suppressor complex and of the SCF ubiquitin-ligase (E3) complex.
Homology Group (KOG)  SCF ubiquitin ligase, Rbx1 component
GO Terms  ubiquitin-protein ligase activity (GO:0004842) ; zinc ion binding (GO:0008270) ; protein ubiquitination (GO:0016567) ; ubiquitin ligase complex (GO:0000151)
Location   V:9691900..9693598
RNAi Phenotypes
Early_embryo Pnm
Larva Lva
Adult Pvl ; Lon ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:172-e6
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Pnm
RNAi Reagent Name & Type Cenix:172-e6 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Pronuclear Migration
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:ZK287.5
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Lon
RNAi Reagent Name & Type sjj_ZK287.5 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:ZK287.5
Embryonic Phenotypes  Emb Penetrance 90 %
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_ZK287.5 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of ZK287.5 Browse using GBrowse
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