Ace View of ZK287.5 | |||||||
ZK287.5 Details | |||||||
Description | The rbx-1 gene encodes an ortholog of the mammalian RING box protein RBX1 (or ROC1), which interacts with several cullins and is a subunit of both the von Hippel-Lindau (VHL) tumor suppressor complex and of the SCF ubiquitin-ligase (E3) complex. | ||||||
Homology Group (KOG) | SCF ubiquitin ligase, Rbx1 component |
||||||
GO Terms | ubiquitin-protein ligase activity (GO:0004842) ; zinc ion binding (GO:0008270) ; protein ubiquitination (GO:0016567) ; ubiquitin ligase complex (GO:0000151) | ||||||
Location | V:9691900..9693598 | ||||||
RNAi Phenotypes |
|
||||||
External Links | |||||||
Associated RNAi Experiments | |||||||
Cenix:172-e6 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | Pnm |
||||||
RNAi Reagent Name & Type | Cenix:172-e6 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: Pronuclear Migration | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
JA:ZK287.5 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
Adult Phenotypes | Lon |
||||||
RNAi Reagent Name & Type | sjj_ZK287.5 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2003-1-10 | ||||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||
Simmer:ZK287.5 | |||||||
Embryonic Phenotypes | Emb Penetrance 90 % | ||||||
Larval Phenotypes | Lva |
||||||
RNAi Reagent Name & Type | sjj_ZK287.5 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Gene Plot of ZK287.5 | |||||||