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Gene/ORF ZK328.5 (npp-10) Ace View of ZK328.5
ZK328.5 Details Help
Description  npp-10 is orthologous to the human gene NUCLEOPORIN, 98-KD (NUP98; OMIM:601021), which can promote leukemias (myelodysplastic syndromes, AML, or CML) when chromosomally rearranged.
Homology Group (KOG)  Nuclear pore complex, Nup98 component (sc Nup145/Nup100/Nup116)
GO Terms  transport (GO:0006810) ; nuclear pore (GO:0005643)
Location   III:6013078..6018236
RNAi Phenotypes
Early_embryo Pronuclear/Nuclear Appearance abnormal
Adult Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:304-b3
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Pronuclear/Nuclear Appearance abnormal
RNAi Reagent Name & Type Cenix:304-b3 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Pronuclear/Nuclear Appearance
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:341-h8
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type Cenix:341-h8 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:ZK328.5
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Ste
RNAi Reagent Name & Type sjj_ZK328.5 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:ZK328.5
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_ZK328.5 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:304b3
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:304b3 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (ZK328.5-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:341h8
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:341h8 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (ZK328.5-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
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