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Gene/ORF ZK381.1 (him-3) Ace View of ZK381.1
ZK381.1 Details Help
Description  him-3 encodes a homolog of the S. cerevisiae HOP1 protein which is required for the formation of the synaptonemal complex during meiosis; him-3 is required for synapsis and chiasma formation during meiotic recombination and for chromosome segregation; him-3 mutants show a high frequency of males in the population as well as a high frequency of arrested embryos due to defects in X-chromosome segregation; HIM-3 localizes to the meiotic chromosome associating with both unsynapsed and synapsed chromosomes.
Homology Group (KOG)  HORMA domain
GO Terms  meiosis I, chromosome segregation (GO:0045143) ; sister chromatid cohesion (GO:0007062) ; synaptonemal complex formation (GO:0007130) ; condensed nuclear chromosome (GO:0000794) ; DNA binding (GO:0003677)
Location   IV:6977103..6979142
RNAi Phenotypes
Adult Him ; Him
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Cenix:15-e9 WT
Experiments with Non-Wild Phenotypes
PF:GL1_4C3 Emb ; Him
JA:ZK381.1 Emb ; Him
Gene Plot of ZK381.1 Browse using GBrowse
Gene Map