Ace View of ZK546.6 | |||
ZK546.6 Details | |||
Description | msp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | ||
GO Terms | structural molecule activity (GO:0005198) | ||
Location | II:4932579..4933833 | ||
RNAi Phenotypes |
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External Links | |||
Associated RNAi Experiments | |||
JA:ZK546.6 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_ZK546.6 (PCR reagent) | ||
Laboratory | JA | ||
Date | 2003-1-10 | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Simmer:ZK546.6:Repeat_a | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_ZK546.6 (PCR reagent) | ||
Laboratory | NL | ||
Date | 2003-10-01 | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Simmer:ZK546.6:Repeat_b | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_ZK546.6 (PCR reagent) | ||
Laboratory | NL | ||
Date | 2003-10-01 | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Simmer:ZK546.6:Screen | |||
Embryonic Phenotypes | Emb Penetrance 20 - 40 % | ||
RNAi Reagent Name & Type | sjj_ZK546.6 (PCR reagent) | ||
Laboratory | NL | ||
Date | 2003-10-01 | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Gene Plot of ZK546.6 | |||