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Gene/ORF ZK637.8 (unc-32) Ace View of ZK637.8
ZK637.8 Details Help
Description  unc-32 encodes six isoforms of a highly conserved vacuolar H+-ATPase a subunit (V-ATPase) homologous to the vertebrate a1 proteins that have been implicated in a number of human diseases including osteopetrosis (OMIM:259700); UNC-32 is predicted to function as part of an ATP-dependent proton pump that regulates acidification of intracellular compartments and is essential for locomotion and embryonic and larval development; UNC-32 is expressed throughout the life cycle, with early and broad expression detectable in the embryo, and larval and adult expression detectable in the gut, gonad, and neurons.
GO Terms  proton transport (GO:0015992) ; membrane (GO:0016020)
Location   III:8905120..8912044
RNAi Phenotypes
Early_embryo Pace of P-Lineage abnormal
Larva Gro
Adult Sck ; Pvl ; Unc ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
JA:ZK637.8 Pvl ; Sck ; Ste
TH:300g5 Emb
TH:341g10 Emb
Cenix:300-g5
Simmer:ZK637.8 Emb ; Gro ; Unc
Cenix:341-g10 Emb ; Pace of P-Lineage abnormal
Gene Plot of ZK637.8 Browse using GBrowse
Gene Map