Ace View of ZK652.9 | |||
ZK652.9 Details | |||
Description | coq-5 encodes a putative ubiquinone biosynthesis methyltransferase, homologous to COQ5 in S. cerevisiae and a family of methyltransferases involved in ubiquinone, menaquinone, biotin and sterol biosynthesis and in phosphatidylethanolamine methylation; COQ-5 is required for ubiquinone biosynthesis and for normally short lifespan; coq-5(RNAi) animals have reduced levels of coenzyme Q8, coenzyme Q9, and superoxide, and have abnormally long lifespans. | ||
Homology Group (KOG) | Ubiquinone biosynthesis methyltransferase COQ5 |
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GO Terms | methyltransferase activity (GO:0008168) ; S-adenosylmethionine-dependent methyltransferase activity (GO:0008757) ; coenzyme biosynthesis (GO:0009108) | ||
Location | III:7856838..7858780 | ||
RNAi Phenotypes |
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External Links | |||
Associated RNAi Experiments | |||
Wild Type RNAi Experiments | |||
Cenix:305-f7 | WT | ||
TH:305F7 | WT | ||
Cenix:179-f10 | WT | ||
Experiments with Non-Wild Phenotypes | |||
[pmid12709403]:coq-4 | Age ; Unclassified | ||
Gene Plot of ZK652.9 | |||