Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
Link to ZK662.4Link to ZK678.1RNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF ZK678.1 (lin-15A) Ace View of ZK678.1
ZK678.1 Details Help
Description  lin-15A encodes a novel, hydrophilic protein; LIN-15A activity is required non-cell autonomously to negatively regulate vulval development; genetic analysis indicates that lin-15A, a class A synMuv gene, functions upstream of the LET-23 receptor tyrosine and redundantly with class B synMuv genes, such as lin-15B and lin-35 Rb and class C synMuv genes such as trr-1 and mys-1; although the lin-15A expression pattern is not yet known, genetic mosaic analysis suggests that, in regulating vulval induction, LIN-15A functions outside of the six vulval precursor cells P(3-8).p, likely acting instead in the surrounding hypodermal tissue.
GO Terms  regulation of cell fate (GO:0042659)
Location   X:15731487..15735705
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:142-f11 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Gene Plot of ZK678.1 Browse using GBrowse
Gene Map