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Gene/ORF ZK686.3 Ace View of ZK686.3
ZK686.3 Details Help
Description  ZK686.3 is orthologous to the putative tumor suppressor N33 (OMIM:601385, associated with homozygous deletion in metastatic prostate cancer and with loss of function in other tumors); ZK686.3 is also homologous to the S. cerevisiae dolichyl-diphosphooligosaccharide-protein glycotransferase gamma chain (34-kD) subunit, OST3.
Homology Group (KOG)  Oligosaccharyltransferase, gamma subunit
Location   III:7767094..7769386
RNAi Phenotypes
Early_embryo Osmotic Integrity defective ; Osmotic Integrity defective
Larva Lva
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:305-a7
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Osmotic Integrity defective
RNAi Reagent Name & Type Cenix:305-a7 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Osmotic Integrity
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:341-g8
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Osmotic Integrity defective
RNAi Reagent Name & Type Cenix:341-g8 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Osmotic Integrity
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:ZK686.3
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_ZK686.3 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:ZK686.3
Embryonic Phenotypes  Emb Penetrance 100 %
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_ZK686.3 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:305a7
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:305a7 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (ZK686.3 -RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:341g8
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:341g8 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (ZK686.3 -RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Gene Plot of ZK686.3 Browse using GBrowse
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