Ace View of ZK863.6 | |||||
ZK863.6 Details | |||||
Description | The dpy-30 gene encodes an essential nuclear protein required for hermaphrodite dosage compensation as well as normal male development; DPY-30 is expressed ubiquitously throughout development and can be detected in two different multiprotein complexes: the SDC complex involved in dosage compensation and a second complex containing NOX-1 (a WD repeat-containing protein) and ASH-2 (a trithorax-related protein) that is homologous to the yeast Set1p complex involved in epigenetic regulation of transcription. | ||||
Homology Group (KOG) | Histone H3 (Lys4) methyltransferase complex, subunit CPS25/DPY-30 |
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GO Terms | dosage compensation, by hypoactivation of X chromosome (GO:0042464) ; locomotion (GO:0040011) ; regulation of body size (GO:0040014) ; tail tip morphogenesis (sensu Nematoda) (GO:0045138) ; nucleus (GO:0005634) ; molecular_function unknown (GO:0005554) | ||||
Location | V:12193706..12195374 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Cenix:38-f10 | |||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:38-f10 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | early embryonic: Clear cut result. | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
JA:ZK863.6 | |||||
Adult Phenotypes | Dpy |
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Adult Phenotypes | Slu |
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RNAi Reagent Name & Type | sjj_ZK863.6 (PCR reagent) | ||||
Laboratory | JA | ||||
Date | 2003-1-10 | ||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||
Gene Plot of ZK863.6 | |||||