Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
Link to ZK863.6.1Link to ZK863.6.2Link to ZK863.6.3Link to ZK863.7RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF ZK863.6 (dpy-30) Ace View of ZK863.6
ZK863.6 Details Help
Description  The dpy-30 gene encodes an essential nuclear protein required for hermaphrodite dosage compensation as well as normal male development; DPY-30 is expressed ubiquitously throughout development and can be detected in two different multiprotein complexes: the SDC complex involved in dosage compensation and a second complex containing NOX-1 (a WD repeat-containing protein) and ASH-2 (a trithorax-related protein) that is homologous to the yeast Set1p complex involved in epigenetic regulation of transcription.
Homology Group (KOG)  Histone H3 (Lys4) methyltransferase complex, subunit CPS25/DPY-30
GO Terms  dosage compensation, by hypoactivation of X chromosome (GO:0042464) ; locomotion (GO:0040011) ; regulation of body size (GO:0040014) ; tail tip morphogenesis (sensu Nematoda) (GO:0045138) ; nucleus (GO:0005634) ; molecular_function unknown (GO:0005554)
Location   V:12193706..12195374
RNAi Phenotypes
Postembryonic Slu
Adult Dpy
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:38-f10 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Clear cut result.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Adult Phenotypes  Dpy
Adult Phenotypes  Slu
RNAi Reagent Name & Type sjj_ZK863.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of ZK863.6 Browse using GBrowse
Gene Map