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RNAi Experiment: [cgc4761]:A1 Ace View of [cgc4761]:A1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F38B2.1 (ifa-1)
Description of "F38B2.1"  IFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum.
Evidence for Inhibition 
Sliding Window Raw score: 107
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F38B2.1" Links  Wormbase NCBI
[cgc4761]:A1 Phenotypes Help with Phenotypes
Larval  Lvl L1 arrest
Phenotype  Unclassified wavy and swollen intestine
[cgc4761]:A1 Experiment Details Ace View
RNAi Reagent & Type  [cgc4761]:A1 (PCR_reagent)
Reference  Karabinos A et al. (2001) Proceedings of the National Academy of Sciences USA "Essential roles for four cytoplasmic intermediate filament proteins in ...."
Delivery Method  Injection
Date  2001-7-03
Gene Plot of F38B2.1 Browse using GBrowse
Gene Graph