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RNAi Experiment: [cgc5214]:hda-1 Ace View of [cgc5214]:hda-1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C53A5.3 (hda-1)
Description of "C53A5.3"  The hda-1 gene encodes a histone deacetylase 1, similar to histone deacetylases RPD3 from yeast and fly; maternal and zygotic expression of hda-1 is required for embryonic viability, and zygotic expression of hda-1 is also required for gonadogenesis and vulval development.
KOG Annotation  Histone deacetylase complex, catalytic component RPD3
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1719
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C53A5.3" Links  Wormbase NCBI
[cgc5214]:hda-1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Adult  Gon the surviving animals are sterile and display multiple defects in gonadogenesis; a prominent phenotype is the lack of organized somatic gonad structures
[cgc5214]:hda-1 Experiment Details Ace View
Laboratory  YS
RNAi Reagent & Type  yk109d9 (cDNA_reagent)
Strain  N2
Reference  Dufourcq P et al. (2002) Molecular and Cellular Biology "Functional requirement for histone deacetylase 1 in"
Delivery Method  Injection
Date  2002-3-03
Gene Plot of C53A5.3 Browse using GBrowse
Gene Graph