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RNAi Experiment: [cgc5224]:cdk-7.1 Ace View of [cgc5224]:cdk-7.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y39G10AL.3 (cdk-7)
Description of "Y39G10AL.3"  The cdk-7 gene encodes a cyclin-dependent kinase orthologous to human CDK7 (OMIM:601955) that is a component of the general transcription factor IIH (TFIIH) complex; CDK-7 is required during embryogenesis for mRNA transcription and phosphorylation of RNA polymerase II on serine 2 and serine 5, as well as for cell cycle progression, maintenance of ploidy, and completion of meiosis following fertilization.
KOG Annotation  Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1027
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y39G10AL.3" Links  Wormbase NCBI
[cgc5224]:cdk-7.1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
[cgc5224]:cdk-7.1 Experiment Details Ace View
Laboratory  JH
RNAi Reagent & Type  [cgc5224]:cdk-7 (cDNA_reagent)
Strain  N2
Reference  Wallenfang MR et al. (2002) Proceedings of the National Academy of Sciences USA "cdk-7 is required for mRNA transcription and cell cycle progression in ...."
Delivery Method  Bacterial_feeding
Date  2002-2-27
Gene Plot of Y39G10AL.3 Browse using GBrowse
Gene Graph