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RNAi Experiment: [cgc5235]:itr-1.2 Ace View of [cgc5235]:itr-1.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F33D4.2 (itr-1)
Description of "F33D4.2"  itr-1 encodes a putative inositol (1,4,5) trisphosphate receptor that affects the defecation cycle and pharyngeal pumping, and also affects ovulation in a pathway downstream of LET-23; interacts with UNC-54 in vivo, and is expressed in the adult intestine, pharynx, excretory cell, germ line, and spermatheca, with limited neuronal expression.
KOG Annotation  Inositol 1,4,5-trisphosphate receptor
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 677
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F33D4.2" Links  Wormbase NCBI
[cgc5235]:itr-1.2 Phenotypes Help with Phenotypes
Phenotype  Unclassified itr-1 RNAi results in slower pharyngeal pumping in the presence of food; pumping rate is increased in response to serotonin, but is not fully restored to wild-type levels
[cgc5235]:itr-1.2 Experiment Details Ace View
Laboratory  HB
RNAi Reagent & Type  [cgc5235]:itr-1.2 (cDNA_reagent)
Strain  N2
Reference  Walker DS et al. (2002) Molecular Biology of the Cell "Regulated disruption of inositol 1,4,5-trisphosphate signaling in ...."
Delivery Method  Bacterial_feeding
Date  2002-1-18
Gene Plot of F33D4.2 Browse using GBrowse
Gene Graph