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RNAi Experiment: [cgc5259]:ptp-3 Ace View of [cgc5259]:ptp-3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C09D8.1 (ptp-3)
Description of "C09D8.1"  ptp-3 encodes a receptor-like tyrosine phosphatase orthologous to the LAR (Leukocyte Common Antigen Related, OMIM:179590) subfamily of receptor-like tyrosine phosphatases that contain extracellular immunoglobulin-like and fibronectin type III domains and have been implicated in linking cell adhesion to intracellular phosphotyrosine levels; PTP-3 plays a role in gastrulation and epidermal development and functions partly redundantly with the VAB-1 Eph receptor and ephrins VAB-2 and EFN-4 to regulate embryonic morphogenesis; PTP-3 is expressed in many tissues during early embryogenesis, but expression later becomes localized to neuronal processes and epithelial adherens junctions.
Evidence for Inhibition 
Sliding Window Raw score: 1192
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C09D8.1" Links  Wormbase NCBI
[cgc5259]:ptp-3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Morphology defect larval abnormalities averaged 1.1% (range 0 to 9.1%)
[cgc5259]:ptp-3 Experiment Details Ace View
Laboratory  MT
RNAi Reagent & Type  [cgc5259]:ptp-3 (cDNA_reagent)
Strain  N2
Reference  Harrington RJ et al. (2002) Development "The C. elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph ...."
Delivery Method  Injection
Date  2002-1-16
Gene Plot of C09D8.1 Browse using GBrowse
Gene Graph