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RNAi Experiment: [cgc5260]:cye-1:2 Ace View of [cgc5260]:cye-1:2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C37A2.4 (cye-1)
Description of "C37A2.4"  cye-1 encodes a homolog of the G1 cell cycle regulator cyclin E; CYE-1 is required for progression through the G1 phase of the cell cycle and for endoreduplication in intestinal cells, and is required maternally both for embryonic development and for the proper execution of several post-embryonic lineages (e.g. vulval development); CYE-1 is provided maternally and expressed ubiquitously in nuclei during embryonic development; postembryonic expression is restricted to actively proliferating blast cells, including the germline.
Evidence for Inhibition 
Sliding Window Raw score: 1440
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C37A2.4" Links  Wormbase NCBI
[cgc5260]:cye-1:2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 15 - 50 %
Larval  Lva
Phenotype  Unclassified the extra intestinal cell phenotype was suppressed from 38(+-3) in cdc-25.1(gf) mutants alone, to 20 (+-5) in cdc-25.1(gf); cye-1(RNAi) animals
[cgc5260]:cye-1:2 Experiment Details Ace View
RNAi Reagent & Type  [cgc5260]:cye-1 (cDNA_reagent)
Strain  MR142
Reference  Kostic I et al. (2002) Development "Organ-specific cell division abnormalities caused by mutation in a general cell ...."
Delivery Method  Injection
Date  2002-2-08
Gene Plot of C37A2.4 Browse using GBrowse
Gene Graph