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RNAi Experiment: [cgc5261]:pat-4 Ace View of [cgc5261]:pat-4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C29F9.7 (pat-4)
Description of "C29F9.7"  The pat-4 gene encodes a serine/threonine kinase orthologous to human integrin-linked kinase (ILK, OMIM:602366) and is required for formation of integrin-mediated muscle cell attachments during embryogenesis; PAT-4 probably functions as an adaptor molecule and localizes to dense bodies and M lines; PAT-4 forms a ternary complex with PAT-6/actopaxin and UNC-112, and requires UNC-112, UNC-52/perlecan, PAT-2/alpha integrin, and PAT-3/beta integrin for proper localization to newly forming integrin adhesion complexes.
KOG Annotation  Integrin-linked kinase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1347
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C29F9.7" Links  Wormbase NCBI
[cgc5261]:pat-4 Phenotypes Help with Phenotypes
Embryonic  Pat
[cgc5261]:pat-4 Experiment Details Ace View
Laboratory  WB
RNAi Reagent & Type  yk199a2 (cDNA_reagent)
Strain  N2
Reference  Mackinnon AC et al. (2002) Current Biology "C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion ...."
Delivery Method  Injection
Date  2002-3-07
Gene Plot of C29F9.7 Browse using GBrowse
Gene Graph