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RNAi Experiment: [cgc5340]:msh-6 Ace View of [cgc5340]:msh-6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y47G6A.11 (msh-6)
Description of "Y47G6A.11"  msh-6 is orthologous to the human gene MUTS (E. COLI) HOMOLOG 6 (MSH6; OMIM:600678), which when mutated leads to disease.
KOG Annotation  Mismatch repair ATPase MSH6 (MutS family)
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 664
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y47G6A.11" Links  Wormbase NCBI
[cgc5340]:msh-6 Phenotypes Help with Phenotypes
Phenotype  Mut RNAi results in an increased spontaneous mutation frequency in the germline and somatic DNA instability
[cgc5340]:msh-6 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  [cgc5340]:msh-6 (cDNA_reagent)
Strain  BC1958
Remark  injection of dsRNA produced identical results
Reference  Tijsterman M et al. (2002) Genetics "Frequent germline mutations and somatic repeat instability in DNA ...."
Delivery Method  Bacterial_feeding
Date  2002-3-09
Gene Plot of Y47G6A.11 Browse using GBrowse
Gene Graph