Link to F53H4.1RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
RNAi Experiment: [cgc5346]:csb-1 Ace View of [cgc5346]:csb-1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F53H4.1 (csb-1)
Description of "F53H4.1"  csb-1 is orthologous to human gene ERCC6 (OMIM:133530, mutated in Cockayne syndrome); CSB-1 is required for embryonic viability, and represses UV-induced apoptosis in germ cells.
KOG Annotation  Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain)
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 2035
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F53H4.1" Links  Wormbase NCBI
[cgc5346]:csb-1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Unclassified csb-1 RNAi results in an increased UV-induced apoptosis in the germ cells
[cgc5346]:csb-1 Experiment Details Ace View
RNAi Reagent & Type  yk646a6 (cDNA_reagent)
Strain  WT
Reference  Lee MH et al. (2002) FEBS Letters "The gene expression and deficiency phenotypes of Cockayne syndrome B protein in ...."
Delivery Method  Injection
Date  2002-5-07
Gene Plot of F53H4.1 Browse using GBrowse
Gene Graph