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RNAi Experiment: [cgc5553]:pas-1 Ace View of [cgc5553]:pas-1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C15H11.7 (pas-1)
Description of "C15H11.7"  pas-1 encodes a type 6 alpha subunit of the 26S proteasome's 20S protease core particle (CP); PAS-1 is required for embryonic development and by homology, is predicted to comprise the outer rings of the proteasome and to play a role in selective degradation of ubiquitinated proteins during development; in vitro, PAS-1 interacts with VET-1, a coiled-coil domain-containing protein expressed in the early embryo and ATN-1, an alpha-actinin, in addition to other members of the proteasome.
KOG Annotation  20S proteasome, regulatory subunit alpha type PSMA6/SCL1
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 678
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C15H11.7" Links  Wormbase NCBI
[cgc5553]:pas-1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
[cgc5553]:pas-1 Experiment Details Ace View
RNAi Reagent & Type  [cgc5553]:C15H11.7 (cDNA_reagent)
Reference  Takahashi M et al. (2002) Biological Chemistry "Reverse genetic analysis of the Caenorhabditis elegans 26S proteasome subunits ...."
Delivery Method  Bacterial_feeding
Date  2002-7-01
Gene Plot of C15H11.7 Browse using GBrowse
Gene Graph