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RNAi Experiment: [cgc5553]:pbs-4 Ace View of [cgc5553]:pbs-4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T20F5.2 (pbs-4)
Description of "T20F5.2"  pbs-4 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-4 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-4 activity via RNAi indicates that, in C. elegans, PBS-4 is required for embryonic, germline, and larval development.
KOG Annotation  20S proteasome, regulatory subunit beta type PSMB2/PRE1
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 525
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T20F5.2" Links  Wormbase NCBI
[cgc5553]:pbs-4 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
[cgc5553]:pbs-4 Experiment Details Ace View
RNAi Reagent & Type  [cgc5553]:T20F5.2 (cDNA_reagent)
Reference  Takahashi M et al. (2002) Biological Chemistry "Reverse genetic analysis of the Caenorhabditis elegans 26S proteasome subunits ...."
Delivery Method  Bacterial_feeding
Date  2002-7-01
Gene Plot of T20F5.2 Browse using GBrowse
Gene Graph