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RNAi Experiment: [cgc5553]:rpn-2 Ace View of [cgc5553]:rpn-2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C23G10.4 (rpn-2)
Description of "C23G10.4"  rpn-2 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory paritcle (RP) base subcomplex; RPN-2 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation; RPN-2 is expressed sporadically at all stages of development in the pharynx, intestine, body wall muscle, somatic gonad, neurons, and hypodermis.
KOG Annotation  26S proteasome regulatory complex, subunit RPN2/PSMD1
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1923
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C23G10.4" Links  Wormbase NCBI
[cgc5553]:rpn-2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
[cgc5553]:rpn-2 Experiment Details Ace View
RNAi Reagent & Type  [cgc5553]:C23G10.4 (cDNA_reagent)
Reference  Takahashi M et al. (2002) Biological Chemistry "Reverse genetic analysis of the Caenorhabditis elegans 26S proteasome subunits ...."
Delivery Method  Bacterial_feeding
Date  2002-7-01
Gene Plot of C23G10.4 Browse using GBrowse
Gene Graph